British Air Force Typhoon FGR4s have joined forces with French warplanes in a combined operation on an underground arms cache in Syria used by the IS group, according to the UK's MoD.
The site, identified by intelligence, was believed to be containing munitions and bombs, the release indicated, and was positioned in mountainous terrain just above the historic site of Palmyra in the heart of Syria.
"The RAF jets employed precision-guided Paveway IV munitions to strike a number of entry passages providing entry to the facility... initial indications indicate the strike was effective," officials stated.
There was no sign of any harm to civilians in the operation late on Saturday and every plane involved returned to base without incident, the ministry further stated.
The British jets were assisted by a Voyager tanker plane.
The Islamic State group - alternatively referred to as Daesh - enforced jihadist rule over significant areas in Syria and Iraq before its territorial defeat in 2019.
"This action demonstrates the UK's leading role, and resolve to operate in unison with our allies, to eradicate any resurgence of IS and their dangerous and violent ideologies in the region," the British Defence Secretary the minister stated.
British military aircraft have carried out surveillance missions over Syria to "deter any attempted comeback" of the group following its defeat at the battle of Baghuz in 2019, the authorities noted.
"I extend gratitude to every member of our armed forces participating in this mission for their professionalism and their valour," he said. "They were among thousands of UK service members deployed over the holidays. This mission, to eliminate terrorist threats who pose a risk to our security, shows how UK forces are always on standby, throughout the year, keeping Britain secure at home and powerful internationally."
In December, the US military conducted what it described as a "massive strike" on Daesh sites in Syria, subsequent to an ambush killed two US servicemembers and a civilian interpreter in the Palmyra area.
The United Nations reports Daesh still has roughly 5-7 thousand combatants in Iraq and Syria.